Reduction in severity of radiation-induced dermatitis in head and neck cancer patients treated with topical aloe vera gel
In this clinical trial, the authors concluded that topical aloe vera application reduced the severity of radiation-induced dermatitis in head and neck cancer patients being treated with concurrent chemoradiation.
AbstractPurpose: To assess the efficacy of topical aloe vera gel on radiation induced dermatitis (RID) in head and neck cancer (HNC) patients.
Method: In this multicenter randomized double-blind controlled study, HNC patients treated with concurrent chemoradiation (CCRT) received either aloe vera gel or placebo gel. Adverse skin toxicity levels were evaluated with the radiation-induced skin reaction assessment scale (RISRAS).